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Intermediates Product List

Sr. No	Products	Intermediate	CAS #
1	Apixaban	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate	503614-91-3
2	Apremilast	(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt	608141-43-1
3	Aprepitant	(2R,3S) -2-[(1R)-1-[3,5-Bis(trifluoromethyl) phenyl] ethoxy]-3-(4-fluorophenly)morpholine hydrochloride (APT07)	171482-05-6
		N-(2-chloro-1-methyl-ethylidene)-hydrazinecarboxylic acid methyl ester	155742-64-6
4	Azelnidipine	1-Benzhydrylazetidin-3-yl 3-amino-3-iminopropanoate acetate	170749-59-4
5	Bazedoxifene	3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole	198479-63-9
		1-(2-(4-(Chloromethyl )phenoxy)ethyl)azepane hydrochloride	223251-25-0
6	Cariprazine HCl	N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea	839712-12-8
7	Cinacalcet	3-(3-Trifluoromethylphenyl)propanol	78573-45-2
		R-(+)-1-(1-Naphthyl)Ethylamine	3886-70-2
8	Clarithromycin	2',4''-O-bis-(trimethylsilyl)-6-O-methylerythromycinA 9-[O-(1-methoxy-1-methylethyl)oxime]	119699-81-9
		Silylated Erythromycin Oxime Ketal	119665-76-8
9	Dabrafenib Mesylate	Methyl 3-(2,6-difluoro-benzenesulfonylamino)-2-fluoro-benzoate	1195768-19-4
10	Droperidol	1-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,3-dihydro-benzoimidazol-2-one	2147-83-3
11	Edoxaban	N1-((1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin- 2-yl)oxalamide	480452-37-7
12	Elexacaftor	2-Chloro-6-[3-(3,3,3-trifluoro-2,2-dimethyl-propoxy)-pyrazol-1-yl]-nicotinic acid tert-butyl ester	2229861-16-7
		2-chloro-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinic acid	2229861-17-8
		2-chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide	2229861-18-9
13	Linagliptin	8-Bromo-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione	853029-57-9
		N-[(3R)-1-[7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]-carbamic Acid 1,1-Dimethylethyl Ester	668273-75-4
14	Mirabegron	(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol	391901-45-4
		2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol Hydrochloride	521284-22-0
15	Niraparib Tosylate	2-Methyl-2-propanyl (3S)-3-(4-bromophenyl)-1-piperidinecarboxylate	1476776-55-2
		Tert-butyl 3-[4-[7-(tert-butylcarbamoyl)-2H-indazol-2-yl]phenyl]piperidine-1-carboxylate	1476776-97-2
16	Pacritinib Citrate	3-Allyloxymethyl-4-(2-pyrrolidin-1-yl-ethoxy)phenylamine	937273-33-1
		[4-(3-allyloxymethyl-phenyl)-pyrimidin-2-yl]-[3-allyloxymethyl-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine	937273-34-2
17	Ponatinib Hydrochloride	3-Iodo-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide	943320-50-1
18	Relugolix	1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-nitrophenyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione,hydrochloride	1589503-95-6
		N-[(2,6-difluorophenyl)methyl]-N-[4-[(dimethylamino)methyl]-3-[[(6-methoxy-3-pyridazinyl)amino]carbonyl]-5-(4-nitrophenyl)-2-thienyl]-, ethyl ester	1589503-94-5
		1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-nitrophenyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione,hydrochloride	1589503-99-0
		1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-aminophenyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione,hydrochloride	1589503-93-4
19	Ribociclib Succinate	2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide	1211443-61-6
		tert-butyl 4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate	1374639-78-7
20	Rivaroxaban	(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride	898543-06-1
21	Selumetinib Sulfate	Methyl 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylate	606144-02-9
		6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid	606144-04-1
		6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-vinyloxy-ethoxy)-amide	606144-05-2
22	Suvorexant	[(7R)-Hexahydro-7-methyl-4-(phenylmethyl)-1H-1,4-diazepin-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone;	1620097-07-5
		(R)-(7-methyl-1,4-diazepan-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone	1030377-32-2
23	Telotristat Ethyl	(R)-1-[4-Chloro-2-(3-methyl-pyrazol-1-yl)-phenyl]-2,2,2-trifluoro-ethanol	1033805-26-3
		2-(S)-Amino-3-[4-(2-amino-6-{R-1-[4-chloro-2-(3-methyl-pyrazol-1-yl)-phenyl]-2,2,2-trifluoro-ethoxy}-pyrimidin-4-yl)-phenyl]-propionic acid	1033805-28-5
24	Tofacitinib Citrate	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	477600-74-1
25	Trametinib Dimethyl Sulfoxide	3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione	871700-07-1
		N-{4-[3-Cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydro-pyrido[2,3-d]pyrimidin-5-ylamino]-phenyl}-acetamide	871700-25-3
26	Vemurafenib	N-{3-[(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-oxo-methyl]-2,4-difluoro-phenyl}-propane-1-sulfonamide	918504-27-5
27	Vismodegib	2-(2-Chloro-5-nitro-phenyl)-pyridine	879088-40-1
		4-Chloro-3-pyridin-2-yl-phenylamine	879088-41-2